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Gastric or duodenal ulcers occur when acids that help us digest food damage the walls of the stomach or duodenum. The most common cause is infection with a bacterium called Helicobacter pylori. Another cause is the prolonged use of anti-inflammatory drugs such as acetylsalicylic acid or ibuprofen, as acidic substances are highly irritating to the mucosae.
The primary symptom is pain in the epigastrium (upper abdomen), with a postprandial predominance (after a meal) or at bedtime, as well as nausea, vomiting and weight loss.
The most serious complications of such ulcers are gastrointestinal bleeding (HDH) and bowel perforation causing peritonitis (irritation of the peritoneum by intestinal acid content and germs).
