Digestive 
Blood
Cardiovascular
Dermatology
Genitourinary,
Hormones
Infections
Oncology and
Musculo-skeletal
Mental health and
Parasites
Respiratory
Senses
Various
The main symptoms are bleeding and thrombosis.
Bleeding can occur at any location, including epistaxis (nosebleeds) and bleeding gums and the gastrointestinal tract.
With this type of disease, the size of other organs of the blood such as the spleen (splenomegaly) and liver (hepatomegaly) often increase in size.
